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Brain's Axons Are Extremely Sensitive To Directional Cues

2004-05-26


New Technology Shows Washington, D.C. – Researchers at Georgetown University have developed a novel technology to precisely measure the sensitivity of nerve fibers that wire up the brain during development. Through use of this technology, they discovered that these fibers, or axons, possess an incredible sensitivity to molecular guidance cues that direct the axon's route to its desired destination in the brain. Their findings are described in the June issue of Nature Neuroscience.

Similar to connecting your PC, monitor, mouse and printer correctly to make all computer parts work, the developing brain needs a series of critical wiring connections to be made for it to function properly. But, unlike computers that come with a user and troubleshooting manual, nerve fibers called axons must follow molecular cues to find the right targets.

http://www.sciencedaily.com/releases/2004/05/040524060425.htm
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